Anti-Infectives Week

Allergy & Immunology - Interferon-alpha stimulates an anti-viral protein in human hepatocytes

Drug Development - Topical antifungal agent for onychomycosis demonstrates good safety profile

Drug Resistance - Methicillin-resistant Staphylococcus is linked to in-hospital mortality in cardiac surgical patients

Pharmacology - Pharmacokinetics of anidulafungin in children with neutropenia studied

Vancomycin-Resistant Enterococcus - Epidemic VRE nosocomial spread controlled by strict infection control measures

Adverse Drug Reaction - BCG vaccination is linked to septic dislocation of the hip

Adverse Drug Reaction - ICH codes alone are not helpful in evaluating adverse drug reactions

Allergy & Immunology - Antibiotic use in infants may double asthma risk

Antibacterial Agents -  Staphylococcus aureus vulnerability to antibiotic treatment may be linked to location in osteomyelitis

Antibacterial Agents - A novel quinolone and sitafloxacin have potent activity against gram-positive pathogens

Antibacterial Agents - Gentamicin-vancomycin-loaded hip spacers inhibited microbial growth for 2 weeks in vitro

Antibacterial Agents - Patients with intraabdominal infections effectively treated with ertapenem

Antimicrobial Agents - A new streptogramin was bactericidal until target strains acquired an erm gene

Antimicrobial Agents - Intra-abdominal infections treated with moxifloxacin monotherapy

Antimicrobial Agents - Lauric acid and gentamicin may produce a bacteriostatic effect

Antimicrobial Agents - Miltefosine and other antileishmanial drugs analyzed for interactions

Antimicrobial Peptides - Antimicrobial peptides trigger pathogen virulence

Antimicrobial Resistance -  Acinetobacter baumannii isolates expressing OXA-58 carbapenemase widely disseminated in ICU

Antimicrobial Resistance -  Acinetobacter species-expressing bla(OXA-58) carbapenemases geographically widespread

Antimicrobial Resistance -  Enterobactefiaceae isolates producing CTX-M ESBL increasing in Austria

Avian Influenza - U.S. Department of Health orders 1.75 million more courses of anti-viral zanamivir Relenza

Breast Cancer - Breast cancer therapy utilizes retrovirus-mediated tk gene

Business Update - Warnex contracts with AmeriSci Bio-Chem service lab for PCR pathogen testing services

Cardiovascular Research - In atherosclerotic lesions of heart disease patients, diverse bacterial signatures were detected

Cholera Toxin - Cholera toxin induces immunomodulator transcriptional responses

Clinical Trials - Clinical trial shows 96% improvement in pressure ulcer healing among nursing home residents

Clinical Trials - U.S. FDA grants Cerexa fast track designation for PPI-0903

Clostridium Difficile -  Clostridium difficile-associated disease-related treatment risk higher with metronidazole

Collaborations - Albemarle named as Tamiflu production partner

Collaborations - sanofi-aventis and Roche ink deal to produce shikimic acid

Contraceptive Microbicide - HIV infection and fertilization targets exploited for contraceptive microbicide development

Disease Associations - HIV/HCV co-infection follow-up is aided by the use of core antigen-based testing

Disease Associations - Lung cancer prognosis is worse in HIV/AIDS than in general population

Drug Development - Immtech completes U.S. FDA special protocol assessment

Drug Development - Wyeth Pharmaceutical's form of antibiotic tigecycline gets 'positive opinion' in Europe

Drug-Resistant Staphylococcus Aureus - Multidrug-resistant CA-MRSA emergent clones are a major public health concern in Australia

Generic Drugs - Immtech announces DB289's to be named pafuramidine maleate

Genetics & Genomics - Mycobacterial vaccination and infection induces transcriptional responses

Glaucoma - InSite Vision announces positive trial results, prepares for AzaSite NDA

HIV Transmission - Alkyl sulfate microbicides can be used to treat milk from HIV-1-positive women

HIV/AIDS Diagnostics - Discordance between interpretation algorithms for HIV genotypes is subtype dependent

HIV/AIDS Diagnostics - IFN-gamma alone may be insufficient to evaluate breadth of HIV-specific T cell response

HIV/AIDS Diagnostics - Researchers publish new studies and findings in the area of HIV/AIDS diagnostics

HIV/AIDS Drug Adherence - Adherence and response to HAART interaction requires multidisciplinary approach