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HIV/AIDS Therapy

Reports from Centers for Disease Control and Prevention advance knowledge in HIV/AIDS therapy

Published in Anti-Infectives Week, March 19th, 2007

Data detailed in "Evaluation of dried blood spots for human immunodeficiency virus type 1 drug resistance testing" have been presented. "Dried blood spots (DBS) are simpler to prepare, store, and transport than plasma or serum and may represent a good alternative for drug resistance genotyping, particularly in resource-limited settings. However, the utility of DBS for drug resistance testing is unknown," investigators in the United States report.

"We investigated the efficiency of amplification of large human immunodeficiency virus type 1 (HIV-1) pol fragments (1,023 bp) from DBS stored at different temperatures, the type of amplified product(s) (RNA and/or DNA), and...

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