HIV/AIDS

Ultra deep sequencing identifies HIV drug resistance at early stage

Published in Anti-Infectives Week, July 2nd, 2007

Rare, previously undetectable drug-resistant forms of HIV have been identified by Yale School of Medicine researcher Michael Kozal, M.D., using an innovative genome sequencing technology that quickly detects rare viral mutations.

Kozal, associate professor of medicine at Yale and senior author of the retrospective study that used samples from an earlier clinical trial, presented the findings today at the 16th International HIV Drug Resistance Workshop in Barbados. “We found that the fraction of HIV patients that harbored resistance mutations is at least twice as high as previously thought,” said Kozal, who also directs the HIV Program at the VA Connecticut Healthcare...

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Source: Anti-Infectives Week (2007-07-02)

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