Cancer
Research in the area of cancer reported from Z. Shi and colleagues
Published in Anti-Infectives Week, January 28th, 2008
According to a study from Guangzhou, People's Republic of China, "It has been reported that gefitinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), has the ability to modulate the function of certain ATP-binding cassette (ABC) transporters and to reverse ABC subfamily B member I (ABCB1; P-glycoprotein)- and ABC subfamily G member 2 (ABCG2; breast cancer resistance protein/mitoxantrone resistance protein) -mediated multidrug resistance (MDR) in cancer cells. However, it is unknown whether other EGFR TKIs have effects similar to that of gefitinib."
"In the present study, we have investigated the interaction of another EGFR TKI, erlotinib,...
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Source: Anti-Infectives Week (2008-01-28)
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