Life Sciences
Study findings from University Federal of Sao Paulo provide new insights into life sciences
Published in Anti-Infectives Week, April 14th, 2008
Fresh data on life sciences are presented in the report 'A short proregion of trialysin, a pore-forming protein of Triatoma infestans salivary glands, controls activity by folding the N-terminal lytic motif.' "Triatoma infestans (Hemiptera: Reduviidae) is a hematophagous insect that transmits the protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas' disease. Its saliva contains trialysin, a protein that forms pores in membranes," investigators in Brazil report.
"Peptides based on the N-terminus of trialysin lyse cells and fold into alpha-helical amphipathic segments resembling antimicrobial peptides. Using a specific antiserum against...
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Source: Anti-Infectives Week (2008-04-14)
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