Colon Cancer

New colon cancer research reported from I. Lelongrebel and co-authors

Published in Anti-Infectives Week, June 2nd, 2008

"Two chemosensitive cell lines, LoVo-fusoid (LoVof) and LoVo-small cells (LoVo-sc) were derived from the original LoVo cell line. These two variants and the multidrug-resistant (MDR) cell line LoVo-Dox were screened for various properties," scientists in Strasbourg, France report.

"In non-permeabilized cells, only LoVo-sc showed mucin-2 staining whereas labelling was positive in all permeabilized cell lines. As shown by electron microscopy screening and by relative resistance to trypsin detachment, only LoVo-sc cells showed strong mucus secretion. All three cell lines displayed strong staining for P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP) and...

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Source: Anti-Infectives Week (2008-06-02)

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