World Journal of Gastroenterology
Is bismuth a safe medicine for the treatment peptic ulcer disease?
Published in Anti-Infectives Week, January 19th, 2009
Bismuth compounds have been used for centuries in medicine. The discovery of H. pylori in 1983 led to renewed interest in bismuth compounds, because these were found to successfully treat the infection in combination with antibiotics. However, in the 1970s bismuth salts, used at high doses for prolonged periods, were found to lead to neurotoxicity. There has been no summary of evidence for the toxicity of bismuth when used for short periods as part of H. pylori eradication therapy.
A research article to be published on December 28, 2008 in the World Journal of Gastroenterology addresses this question. The research team led by Professor Paul Moayyedi from McMaster...
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Source: Anti-Infectives Week (2009-01-19)
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