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Anti-Infectives Week

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Acute Pancreatitis



Researchers at St. Orsola-Malpighi University target acute pancreatitis



June 15th, 2009

According to recent research from Bologna, Italy, "The clinical course in acute necrotizing pancreatitis is mainly influenced by bacterial infection of pancreatic and peripancreatic necrosis. The effect of two antibiotic treatments for early prophylaxis was studied in the taurocholate model of necrotizing pancreatitis in the rat."

"Sixty male Sprague-Dawley rats were divided into three pancreatitis groups (15 animals each) and a sham-operated group (15 animals, control group). Pancreatitis was induced by intraductal infusion of 3% taurocholate under sterile conditions. Animals were placed on one of two different antibiotic regimens (15 mg/kg ertapenem or 20 mg/kg...


Source: Anti-Infectives Week (2009-06-15)

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