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Peripheral Neuropathy Therapy

Investigators at University of Maryland target peripheral neuropathy therapy

Published in Anti-Infectives Week, August 17th, 2009

A new study, 'Genome-wide screen identifies drug-induced regulation of the gene giant axonal neuropathy (Gan) in a mouse model of antiretroviral-induced painful peripheral neuropathy,' is now available. "Painful peripheral neuropathy is a debilitating complication of the treatment of HIV with nucleoside reverse transcriptase inhibitors (NRTIs). Patients are living longer with these drugs; however many develop excruciating, unremitting, and often treatment-limiting neuropathy that is resistant to conventional pain management therapies," scientists in the United States report.

"Improving patient comfort and quality of life is paramount and depends on a clearer...

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