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Findings from M.M. Mircescu et al in life sciences reported

Published in Anti-Infectives Week, August 31st, 2009

According to a study from the United States, "Alveolar macrophages and neutrophils mediate innate immune defense against the opportunistic fungal pathogen Aspergillus fumigatus and are believed to be essential for host survival following inhalation of fungal spores (conidia). Although alveolar macrophages are postulated to kill inhaled conidia and neutrophils are believed to act against hyphae, the relative contribution of alveolar macrophages and neutrophils to early defense against A. fumigatus remain incompletely defined."

"To more precisely characterize the contributions of alveolar macrophages and neutrophils in antifungal host defense, we selectively depleted each...

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