Drug Resistance

Research from Oregon Health & Science University yields new data on drug resistance

Published in Anti-Infectives Week, August 31st, 2009

According to recent research published in the Journal of Antimicrobial Chemotherapy, "The availability of antimicrobials that may be used for the treatment of infections caused by Neisseria gonorrhoeae has been limited by the emergence of antimicrobial resistance, particularly fluoroquinolone resistance. Few data exist regarding the pharmacodynamics of fluoroquinolone resistance selection in N. gonorrhoeae."

"We used mutant prevention concentration (MPC) testing to define the risk of fluoroquinolone resistance induction in N. gonorrhoeae by ciprofloxacin, levofloxacin and moxifloxacin in a wild-type isolate (ATCC 49226) and its corresponding gyrA mutant...

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Source: Anti-Infectives Week (2009-08-31)

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