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Drug Resistance

Researchers from University of Louisville detail findings in drug resistance

Published in Anti-Infectives Week, November 16th, 2009

According to recent research from the United States, "Emergence of antibiotic-resistant bacteria threatens the continued efficacy of many critical drugs used to treat serious infections. What if such resistant organisms could also act as altruists and ''share'' their resistance with sensitive cohorts without any actual genetic exchange' We competed resistant strains that differ solely in their ability to secrete a plasmid-encoded beta-lactamase."

"Sensitive strains were otherwise isogenic with their resistant counterparts and were either plasmid-free or contained a ''Dummy'' plasmid of roughly the same size as that of the resistance plasmids. Absent antibiotic...

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