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Cystic Fibrosis Therapy

Research data from Mpex Pharmaceuticals update understanding of cystic fibrosis therapy

Published in Anti-Infectives Week, March 1st, 2010

Current study results from the report, 'Effect of oxygen limitation on the in vitro activity of levofloxacin and other antibiotics administered by the aerosol route against Pseudomonas aeruginosa from cystic fibrosis patients,' have been published. According to a study from the United States, "Studies have demonstrated that thickened mucous layers in the lungs of cystic fibrosis (CF) patients contain areas of low oxygen tension. These microaerophilic environments may reduce the activity of aerosol antibiotics used in the management of chronic infection in CF."

"The aim of this study was to compare the MICs of levofloxacin, tobramycin, amikacin, and aztreonam against...

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