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Biotech Business Week

Susan Hasty, Publisher

Table of Contents . . . September 29th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Biotech Business Week | Other Publications

AIDS Therapy - Biopharma inks agreement with Guangdong Medicine Group Corp.

Immunology - CpG motifs can be programmed to stimulate specific immune system activities

Cancer Diagnosis - Data from phase III study of Combidex published

Myocardial Infarction - Government agencies select supplier of automated external defibrillators

Polymer Technology - Guidant acquires technology for drug eluting stent program

Restenosis - Cypher sirolimus-eluting coronary stent demonstrates dramatic improvement

Alzheimer Disease - Galantamine study shows promising results for Alzheimer disease

Alzheimer Disease - Patent issued for new methods to treat AD and other amyloid disorders

Antibiotics - Generic pharmaceutical company licenses clarithromycin XL

Antibiotics - Milestone achieved in development of peptide deformylase inhibitors

Anticancer Agents - Patent issued for antitumor agents

Antisense Technology - Classical antisense PTOs used against key multimodal targets

Antisense Technology - Process helps achieve largest antisense oligonucleotide synthesis scale per run

Atrial Fibrillation - Minnesota company inks agreement with LightWave Ablation Systems

Bioterrorism Agents - Biodefense proteomics collaboration receives NIAID funding

Blood Glucose - Oral efficacy study on a novel antidiabetic agent reported

Blood Transfusion - Trials for investigational pathogen inactivation system halted

Botulism - Joint venture wins $11M award to expedite production of botulinum vaccine

Brain Cancer - Data shows efficacy of using PI3k inhibitor in treating malignant gliomas

Breast Cancer - Data from Theratope vaccine trial to be presented at breast cancer symposium

Cancer Detection - Company licenses colon cancer diagnostic patent rights to LabCorp and Baylor

Cancer Vaccine - Progress in field of cancer vaccines reported

Cardiogenic Shock - CS100 automatic balloon pump cleared by FDA for marketing and launched

Chronic Back Pain - Pain center introduces DRX9000

Collaborations - Chemistry deal signed for development of small-molecule compounds

Collaborations - Pharmaceutical companies team to develop cancer and inflammatory disorder treatments

Collaborations - Pharmaceutical companies to identify drug candidates for an allergy target

Collaborations - Product license agreement signed with Micromet for MT201

Collaborations - Research team formed to accelerate discovery of improved oncology drug candidates

Collaborations - Research, supply, comarketing agreement signed for assay development

Corporate Update - Transgenics company implements restructuring plan

Data Analysis - Alliance targets development of automated gene expression analysis pipeline

Diagnostics - Device company sells 14 stand-up MRIs

Distribution Agreement - MiraiBio to distribute AUTOPURE LS in United States, Central and South America

Divestiture - Henry Schein divests nonstrategic German x-ray film distributor

Drug Delivery - Progress reported in development of new drug delivery device portfolio

Drug Development - Atrix submits eighth ANDA to FDA

Drug Discovery - Inpharmatica secures ADME agreement

Dry Eye - Harvard study connects diet, dry eye

Facilities - Biopharmaceutical complex to be built in Quebec for 2004

Finance - Agreement signed for financing of PET equipment

Finance - Biotech company raises $4.65M in equity financing

Finance - Biotech reaches agreement for private placement of up to 7.15 million new shares

Finance - Cardiology device maker reports sale of stock

Finance - Dawson James Securities initiates coverage of HIV vaccine developer

Finance - Device company confirms no cash dividend on its preferred stock

Finance - Diagnostics company files shelf registration statement

Finance - Medical device maker projects 621% increase in revenues

Finance - Nasal administration company closes $11 million private placement

Finance - Oncology company's common stock to be listed on American Stock Exchange

Finance - Pharmaceutical company announces terms of $135M convertible senior notes

Finance - Reference lab reports substantial gains on record operating results

Finance - Research tools company updates outlook for 2003

Finance - SEC guidance issued on device company's revenue recognition question

Finance - Tissue repair biotech company closes private placement

Funding - Fiber technology company receives US$450K in research and development grants

Funding - Grant awarded to develop hepatitis C virus drug susceptibility assay

Generics - KV Pharmaceutical receives payment on generic product dispute

Genetic Disease Detection - Benefits of WAVE system reviewed at colorectal cancer meeting

Genital Herpes - FDA approves Valtrex caplets for reducing risk of spreading herpes

Genomics - LabCorp announces legal settlement

Glaucoma - GDx VCC developer inks exclusive contract with Vision Source

HIV Entry Inhibition - Phase I trial initiated for new anti-HIV drug candidate AMD070

HIV Prevention - Phase I testing of HIV microbicide initiated

HIV Therapy - Phase I trial of autologous VRX496 modified T cells deemed safe

Heart Disease Diagnosis - Stem-cell company provides cardiac risk assessment calculator

Heart Failure - ALT-711 DIAMOND positive trial data presented at European cardiology meeting

Heart Failure - CHARM Programme demonstrates benefits of Atacand

Heart Failure - Diovan reduces atrial fibrillation by 35%

Heart Valve Technology - Tricentrix Holder launched in U.S.

Hunter Syndrome - Long-term, phase I/II data show clinical improvements in patients

Hypertension - Company completes $2.3 million equity financing

Immunology - Cancer, parasitic, and viral disease vaccine has positive first stage results

Inhaler - First NDA submitted for Easi-Breathe in U.S.

Injectors - Distribution agreement inked for AGRO-JET needle-free injectors in Japan

Kidney Cancer - Partial clinical hold on phase III trials of cancer vaccine Oncophage

Lab Management - IAL Biolytix to implement Watson Laboratory Information Management System

Legal Issues - Federal court rejects Medi-Hut's request for injunction in Syntest suit

Legal Issues - Patents cover proprietary protein crystallization technology

Lice - Inyx to introduce a pharmaceutical head-lice treatment in Ireland

Lung Cancer - Biotargeted radiopharmaceuticals being developed based on mTCR technology

Lung Cancer - Data published showing effectiveness of DNA enzyme expression technology

Market Analysis - Biotech wilts in August, but rally isn't over

Market Research - Pharmaceutical product market research budgets increase up to US$12M

Marketing - Early-stage pharmaceutical marketing averages US$9.5M

Mass Spectrometry - Novel Autoflex TOF/TOF system introduced for proteomics research

Melanoma - Positive, long-term, follow-up data reported from phase I trial of GVAX

Mergers and Acquisitions - AVI BioPharma terminates plan of merger with eXegenics

Mergers and Acquisitions - Company discusses GenSci merger and announces plans to streamline

Mergers and Acquisitions - Device company shareholders approve Zimmer offer

Mergers and Acquisitions - Direct Wireless to acquire genomics company

Mergers and Acquisitions - Drug delivery company responds to Cephalon's unsolicited acquisition proposal

Mergers and Acquisitions - New corporate identity unites two medical instrument companies

Migraine Headache - Agreement signed to commercialize potential injectable migraine treatment

Mucopolysaccharidosis - Animal studies demonstrate normalization of carbohydrate storage in brain tissue

Optic Nerve Regeneration - Class of molecules stimulate optic nerve regeneration

Pain Management - Electrotherapy device provides pain relief for variety of conditions

Pain Therapy - Validation of manufacturing process completed for Chronogesic

Parkinson Disease - Rasagiline plus levodopa reduces time when symptoms are not controlled

Patents - Patent issued covering compositions for neurological disorders

Patents - U.S. patent granted covering technologies directed to microbial enrichment

Personnel - Antibody products company announces new president and chief executive officer

Personnel - Benchimol named senior VP of R&D at life sciences technology company

Personnel - Biopharmaceutical company names new chairman of the board

Personnel - Centrex CEO named to board of directors at biotech company

Personnel - Davila joins board of directors at diagnostics device company

Personnel - Diagnostics company announces new president

Personnel - Dialysis company appoints new chief financial officer

Personnel - Former Pfizer attorney joins OTC pharmaceutical firm

Personnel - Hayden named chief financial officer at pharmaceutical company

Personnel - Pharmaceutical company appoints chief medical officer

Personnel - STS Biopolymers announces new president

Personnel - Schnittker appointed as chief financial officer at oncology company

Personnel - VP of worldwide sales and marketing added at genetics company

Personnel - Zolla-Pazner joins viral advisory board at biotech company

Premenstrual Dysphoric Disorder - FDA approves Paxil CR for severe form of PMS

Prostate Cancer - Danish company signs agreement for cancer markers

Prostate Cancer - FDA clears initiation of phase III registrational trial of satraplatin

Prostate Cancer - FDA grants fast track designation for Provenge

Public Relations - Drug-delivery company retains Stern & Co. for investor and media relations

Radiation - FDA issues notice of allowance for X-ray catheter that provides radiation therapy

Reduced Gastrointestinal Motility - Itax licensed from Abbott Laboratories for $75M

Reorganization - Refractive laser company declares Chapter 11 bankruptcy

Reproductive Health - Agreement signed to market condoms

Robotic Surgery - Denver Children's Hospital first to use pediatric robot surgical system

SARS - Alliance with NIH, USARMID targets discovery of therapeutics against SARS

SARS - Muliferon elicits anti-viral response against SARS in research study

Sports Medicine - Fall team sports injuries high among adolescents

Sterilization - U.S. FDA authorizes commercialization of ozone sterilizer

Stock Listing - Safety syringe company to apply for OTC Bulletin Board

Stress Incontinence - Patent granted for SPARC sling system

Stress Urinary Incontinence - FDA issues approvable letter for Duloxetine

Surgical Equipment - Lifeline announces initial inventory commitments

Therapeutic Vaccines - Update provided on HIV, cancer vaccines, workforce reduction

Training - Companies count on proper training to avoid regulatory notices

Trends - Report: Ion-channel modulators have significant clinical, commercial potential

Trends - Research: Antiaging products demand to reach $29 billion in 2007

Urinary Tract Infection - Early completion of patient recruitment in phase II clinical trial of doripenem

Urinary Tract Infections - Ciprofloxacin GR is as effective as Cipro

Varicose Veins - Rights acquired to endovenous laser treatment patent

Ventilator-associated Pneumonia - FDA grants fast track designation for Iseganan

West Nile Virus - Deal signed to share development of West Nile virus hyperimmune globulin

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