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Biotech Business Week

Susan Hasty, Publisher

Table of Contents . . . January 19th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Biotech Business Week | Other Publications

Anxiety - Effexor XR provides long-term treatment of generalized anxiety disorder

Antibody Drug Conjugates - Exclusive antigen license taken under antibody drug conjugate collaboration

Antifungals - Terbinafine HCl Tablets receives tentative FDA approval

Biodefense - Safe room kit available for home protection

Cardiac Surgery - Company announces blood substitute studies for cardiac surgery

Cardiology - New agreement signed for cardiac safety information services

Cardiovascular Disease - Biopharmaceutical company acquired to develop cardiovascular disease treatments

Cardiovascular Disease - Study shows multivitamin offers cardiovascular risk factor protection

Collaborations - Agreement signed with Mitsubishi for irritable bowel syndrome compound

Collaborations - Alliance pledges to serve people with alpha-1 antitrypsin deficiency

Collaborations - Antibody deal with Amgen restructured

Blood Substitute - Patient enrollment begins for urban ambulance/blood substitute trial

Collaborations - Biotech software company announces deal to distribute database

Collaborations - Deal signed for development of sustained release generic product

Collaborations - Deal with Johnson & Johnson expanded to include obesity

Collaborations - Intellectual property for antibodies binding to IL-12 licensed

Collaborations - License, supply agreement signed for osteoarthritis product

Collaborations - Marketing, communications contract extended with ChainDrugStore.net

Collaborations - Rights assigned from complement research to pharmaceutical company

Collaborations - VaxImmune vaccine adjuvant licensed to Chiron

Colon Cancer - Positive ursodiol disulfate study results reported

Conferences - Company announces participation in healthcare conference

Anti-Infectives - FDA approves manufacturing and marketing of Cefaclor Tablets, Chewable

Coronary Artery Disease - European phase II trial of Hemopure initiated in angioplasty patients

Coronary Artery Disease - FDA panel underscores need for greater understanding of aspirin's benefit

Corporate Update - Biotech company announces 2004 strategic initiatives

Cystitis - Pharmaceutical company receives second milestone payment for launch of Uracyst-S

Disease Prevention - Female OB/GYNs name obesity the greatest threat to women's health

Endometriosis - Nasal leuprolide product could offer noninvasive treatment for endometriosis

Epilepsy - Companies enter broad agreement covering topiramate

Esophageal Candidiasis - EMEA marketing application filed for anidulafungin

Finance - Biopharmaceutical company completes stock redemption; files shelf registration

Finance - Cardiology company completes $3.1M private placement

Diabetes Prevention - Diet high in magnesium lowers diabetes risk

Finance - DNA expression technology company to trade on Berlin Stock Exchange

Finance - Medical device company closes $12 million series B financing

Finance - New registration statement filed for initial public offering

Finance - Pharmaceutical company announces change to earnings guidance

Finance - Pharmaceutical company announces exercise of over-allotment option

Finance - Pharmaceutical company completes $35M private placement

Finance - Pharmaceutical company files universal shelf registration statement

Finance - Small protein company raises $1.2 million

Funding - Council would strengthen European research

Generic Drugs - Litigation status updated; FDA approves generic metolazone

Drug Development - New antibody collaboration announced

Genomics - License for patented gene targeting technology granted

Gout - New drug application submitted for Oxyprim

HIV Testing - Uni-Gold Recombigen HIV test receives FDA approval

Heart Disease - Primary endpoints met in phase I/II clinical trial of DX-88

Heart Failure - Triage B-type natriuretic peptide test approved for use on Beckman Coulter platforms

Hepatitis Virus - Antiseptic hand spray formula proven to kill hepatitis A, B and C viruses

Hypertension - Remodulin receives preliminary notice of approval in Switzerland and Australia

Influenza - BCBSNC gives North Carolina Health Departments $300,000 for flu vaccines

Inhaled Insulin - Human trials of Alveair insulin pulmonary technology about to begin

Leg Ulcers - Premarket approval application to be filed for venous leg ulcer treatment

Tumor Growth - Small molecule shown to inhibit tumor growth in preclinical models

Legal Issues - Biotech patent dispute settled

Medical Technology - Global healthcare technology company chooses parts management company

Meningococcal Meningitis - BLA submitted for approval of Menactra

Mergers and Acquisitions - Biopharmaceutical service company acquired

Mergers and Acquisitions - Drug discovery companies announce merger

Mergers and Acquisitions - European pharmaceutical sales, marketing business sold for $120M

Mergers and Acquisitions - Express Scripts, CuraScript announce acquisition agreement

Mergers and Acquisitions - Implant product manufacturer announces termination of acquisition negotiations

Mergers and Acquisitions - Pharmaceutical firms receive FTC request for information on transactions

Multiple Myeloma - Breakthrough discovery puts researchers closer to cure for multiple myeloma

AIDS Therapy - DSMB recommends continuation of phase I trial with VRX496 modified T cells

Multiple Myeloma - Thalidomide Pharmion approved in New Zealand

Myelodysplastic Syndrome - Enrollment stopped for myelodysplastic syndromes monotherapy trial

Myelodysplastic Syndrome - New drug application submitted to market myelodysplastic syndromes therapy

Myocardial Infarction - Company seeks new drug indication for treatment of heart attack survivors

Personnel - Biotech firm appoints renowned biochemist to scientific advisory board

Personnel - Cardiovascular drug development company announces election of directors

Personnel - Chief financial officer resigns from biotech firm

Personnel - Pain management company announces executive appointments

Personnel - Pharmaceutical company announces new chief business officer

Personnel - Pharmaceutical company founder and chairman steps down to nonexecutive role

Acne - New drug application submitted for Actiza

Personnel - Rosa named VP, strategic development at molecular fingerprinting company

Personnel - Silverstein joins board of directors at pharmaceutical company

Personnel - Therapeutics company announces management changes, promotions

Personnel - Two new board members named at drug delivery company

Podiatric Surgery - Study shows reduced pain and narcotic use following foot and ankle surgery

Prostate Cancer - Cancer vaccine manufacturer obtains rights to Biogen Idec LFA-3 patents

Prosthetics - Hydraulic knee frame reintroduced to market

Psoriasis - PVAC program is discontinued due to lack of clinical benefit

Restenosis - Positive phase II clinical results reported in trial of Resten-NG

Rosacea - Finacea 15% gel approved in E.U. countries

Angina - U.S. Food and Drug Administration advisory committee evaluates Ranexa

Urinary Tract Infections - Phase III trial begins with Doripenem in complicated urinary tract infections

Vaccines - Investigational new drug application to be filed for HIV vaccine

Venous Thromboembolism - New drug application submitted to FDA for Exanta

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