Biotech Business Week
Susan Hasty, Publisher
Table of Contents . . . March 8th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Biotech Business Week | Other Publications
Melanoma - Data on autologous cell vaccine published
Virology - A new expression vector augments the cloning of full-length HBV genomes
Avian Influenza - New approach may provide prompt recovery from bird flu
Drug Delivery - Company enters R&D agreement to develop a topical gel for treating pain
Mergers and Acquisitions - Acquisition gives Nanogen foothold in point-of-care diagnostics market
Viral, Bacterial Detection - SMD technology plus lab card device to provide diagnosis of organisms
AIDS Therapy - Data presented on potential new class of antiretroviral therapy
Acne - Laser therapy prevents acne from graduating to scars
Allergy - Contact dermatitis on face could be caused by variety of allergens
Alzheimer Disease - Broad patent granted for neurologic gene therapy
Alzheimer Disease - Cathepsin B identified as important in mediating nerve cell death
Alzheimer Disease - Survey finds gaps in public's knowledge of treatments for AD
Anesthesia - Skin permeation device facilitates rapid skin anesthesia within 5 minutes
Anxiety - In-silico anxiety drug to undergo phase I clinical trials
Asthma - Survey finds many women stop or reduce asthma drugs during pregnancy
Automated External Defibrillators - External defibrillators move into retailing via Walgreens online
Bioinformatics - Ingenuity's products licensed for drug discovery
Blood Banking - Therapeutic company files five patent infringement lawsuits
Breast Cancer - Breast surgeons' group to lead MammoSite RTS patient registry
Breast Cancer - Folate-targeted lipid-based gene vectors reduce breast adenocarcinoma volume
Breast Cancer - New breast cancer test introduced
Breast Cancer - Phase III study of RSR13 initiated in women with brain metastases
Breast Cancer - Study finds nipple-sparing mastectomy is a reasonable option for certain patients
Business & Finance - Pharmaceutical alliances result in greater profits, reports analyst
Business & Finance - Pharmaceutical company signs agreement to promote Riomet
Business Update - Collaboration provides financial services for consumer-driven healthcare
Business Update - European sales for expanded for oncology sales
Business Update - Levulan PDT generates excitement at AAD meeting
Cancer Research Award - Pan-Mass Genomic Services grant awarded to help fund cancer research
Cancer Therapy - Gutless vectors encoding transgenes enhance the effect of oncolytic viruses
Cancer Therapy - Vascular targeting agent technology reviewed in medical journal
Cervical Cancer - Hycamtin-cisplatin regimen shows cervical cancer survival advantage
Chronic Obstructive Pulmonary Disease - Daxas submitted for European approval
Cloning - Cloned stem cells regenerate heart muscle following a heart attack
Collaborations - Development, sales, support agreement signed with Applied Biosystems
Collaborations - Emory, partner, identify topical microbicides for drug development
Collaborations - GPC Biotech achieves milestone in osteoarthritis alliance
Collaborations - High-throughput medicinal chemistry deployed in alliance
Collaborations - Manufacturing, business development partner named for m-doc technology
Collaborations - Merck enters alliance to develop and commercialize gaboxadol for sleep disorders
Collaborations - Milestone payment received from licensing agreement with Pfizer
Collaborations - Mouse genetics deal signed to generate mice for gene function analysis studies
Collaborations - Negotiations proceed on deal to formulate new type of aspirin
Collaborations - PET supplier reports renewal of supply, license agreements with Merck
Collaborations - Premier enters contract for supply of medical gases
Collaborations - Research milestone reached in deal with Amgen
Coughing - Chronic cough significantly impacts life quality in women
DNA Variants - System introduced for DNA sequence variation studies
Diagnostics - The LCx HCV RNA quantitative assay possesses several key attributes
Diagnostics - The in vivo chamber angiogenesis assay measures angiogenic activity in mice
Dialysis - FDA clears SpeedLyser infusion catheter
Drug Delivery - ANDA filed for Toprol-XL; generic version of Lotensin launched
Drug Delivery - Aeroneb Go Nebulizer introduced in U.S.
Drug Delivery - Study shows effective transdermal delivery of testosterone
Drug Discovery - Drug discovery and pharmaceutical companies sign research agreement
Drug Discovery - Lab filters earn Zymark/Caliper exclusive certification
Drug Discovery - New, nonradioactive screen for antimalarial compounds developed
Endometrial Cancer - Estrogen replacement therapy associated with low endometrial cancer recurrence
Enzymology - Peptidyl-alpha-ketoamide inhibitors take unusual steps to block HCV protease
Fabry Disease - Replagal receives Canadian approval to treat Fabry disease
Finance - Band-Aid maker reports 40% increase in revenues
Finance - Biomaterials company reports 49% increase in product sales
Finance - Biopharmaceutical company announces initial public offering
Finance - Biopharmaceutical company reports earnings of $1.44 per share
Finance - Bioscience company reports 2003 financial results
Finance - Biotech company reports 19% revenue growth for 2003
Finance - Biotech firm completes $2.5M revolving credit, security agreement
Finance - Blood products firm reports repayment of debentures
Finance - Cancer drug maker reports loss of $0.18 per share
Finance - Cardiovascular disease drug maker reports loss of $1.21 per share
Finance - Contract research services company reports 26% revenue increase
Finance - Defibrillator maker secures line of credit
Finance - Device company secures new financing, announces expansion
Finance - Device firm reports revenue growth, quarterly earnings
Finance - Device maker reports sales of $2.3M in fourth
Finance - Diagnostic products manufacturer announces positive 2003 financials
Finance - Diagnostics maker reports 10.3% decrease in sales
Finance - Diagnostics maker reports 9.5% increase in revenue
Finance - Drug delivery company reports 8.6% decrease in contract revenue
Finance - Drug delivery company's debt upgraded by Moody's
Finance - Gene-variation company reports fourth quarter and year end results for 2003
Finance - Genomics company prices private placement of $100M notes
Finance - Healthcare product supplier to China reports loss of $0.10 per share
Finance - Hemophilia treatment developer reports yearly loss of $1.28 per share
Finance - Higher revenue, earnings reported by medical device firm
Finance - Immunotherapeutics firm announces $25M in equity financing
Finance - Implant company's 2003 revenues increase by 20% over 2002
Finance - Inflammatory diseases drug maker reports quarterly loss of $0.43 per share
Finance - Life sciences company raises an additional $1.15 million
Finance - Medical device manufacturer announces 2003 financial results
Finance - Medical products manufacturer announces 2003 financial results
Finance - Mitsui makes equity investment in proteomics company
Finance - Neuroscience company reports net loss of $0.02 per share
Finance - Nutritional supplements developer reports fiscal second quarter results
Finance - Ophthalmic pharmaceutical company announces completion of financing round
Finance - Ophthalmology company receives first round financing
Finance - Pennsylvania biotech greenhouse invests $3M in regional enterprises
Finance - Pharmaceutical company announces 2003 financial results
Finance - Pharmaceutical company board announces stock split
Finance - Pharmaceutical company reports 2003 financial results
Finance - Pharmaceutical company reports loss of $0.09 per share
Finance - Pharmaceutical company reports loss of $0.29 per share
Finance - Pharmaceutical firm moves to NASDAQ market under new symbol
Finance - Private pharmaceutical company receives $15.3 million in series A financing round
Finance - Product revenues increase 17% for cardiovascular device maker
Finance - Respiratory care products company reports profitable 2Q
Finance - Sales grow 13.7% for pharmaceutical company
Generic Drugs - Company announces approval and launch of benazepril hydrochloride tablets
HIV Diagnosis - FDA clearances granted for ViroSeq HIV-1 genotyping system
HIV/AIDS Pain - NGX-4010 demonstrates pain reduction in HIV-associated neuropathy study
HIV/AIDS Treatemnt - Human clinical trials of HIV maturation inhibitor to commence
HIV/AIDS Treatment - Phase II HIV study results of Reverset announced
Heart Disease - FDA requests additional information on decellularized heart valves
Heart Failure - Rights acquired to a key cardiac marker, NT-proBNP
Hemodialysis - Dialysate iron therapy for hemodialysis patients receives patent
Hepatitis C Virus - Vaccine possible for multiple strains of hepatitis C, evidence shows
Hypertension - Benazepril Hydrochloride Tablets approved for marketing
Hypertension - FDA plans expedited evaluation of AmVaz NDA
Hypertension - Phase II trial of ALT-711 initiated in endothelial function
Hypertension - Superior blood pressure control reported with use of treatment algorithm
Immunoassays - Eleven diagnostic assays approved for hepatitis, PSA, alpha-fetoprotein
Influenza - Report finds inactivated influenza virus vaccines effective in children
Information Technology - Antibacterials developer selects software for chemical reaction planning
Information Technology - New patient-monitoring system helps improve patient care
Irritable Bowel Syndrome - Awareness, understanding of IBS key to promoting new drugs
Kidney Failure - BMP-7 prevents bone disease in a model of chronic kidney failure
Laboratory Systems - Johns Hopkins installs six BenchMark XT systems
Leukemia - Generic Purinethol tablets receive marketing clearance
Lung Cancer - Lung cancer compound phase II trial commences
Market Analysis - Advanced wound care dressings to be growth engine of European market
Market Analysis - Healthcare costs tops list of Americans' concerns
Market Analysis - Healthcare spending growth projected to nearly double in next decade
Medicare - Choosing hospice care raises federal program costs for last year of life
Meningitis - Health groups recommend temporary suspension of pediatric vaccine dose
Menopause - FDA approves EstroGel transdermal gel for estrogen therapy
Menopause - Hot flashes, night sweats treatment now available in U.S. pharmacies
Mergers and Acquisitions - Acquisition of Applied Molecular Evolution complete
Mergers and Acquisitions - Agreement signed to be acquired by Fisher Scientific
Mergers and Acquisitions - China-based pharmaceutical company acquired
Mergers and Acquisitions - FTC clears way for merger of drug benefits companies
Mergers and Acquisitions - GTCR Golder Rauner announces acquisition
Mergers and Acquisitions - Genome Therapeutics merger complete; merged company focused on anti-infectives
Mergers and Acquisitions - Harvard inks letter of intent to acquire assets of antibody development company
Mergers and Acquisitions - HepatoTech's cell culture business acquired
Mergers and Acquisitions - Invitrogen completes acquisition
Mergers and Acquisitions - Microwave surgical cardiac ablation developer acquired by Guidant
Mergers and Acquisitions - SJ Strategic Investments will not pursue acquisition proposal
Mergers and Acquisitions - University of Pittsburgh Medical Center acquires biotechnology firm
Nanomedicine Trends - Nanobiotech pioneers predict nanomedicine impact within 5 years
Nutrition - Food pyramid recommendations made to U.S. Congress
Nutrition - Group suggests dietary intake levels must be realistic for consumers
Ophthalmic Antibiotic - FDA approves Neomycin, Polymyxin B Sulfates, Bacitracin Zinc ophthalmic ointment
Patents - Key nanotechnology patent issued
Patents - Patent issued for exosome technology - a new approach to immunology
Peripheral Artery Disease - IND Application filed for peripheral artery disease therapy
Personnel - Ahmed named senior VP of global productivity at drug discovery firm
Personnel - Ashleigh Palmer named new chief business officer at biotech company
Personnel - Biomaterials company announces sales and marketing organization changes
Personnel - Biopharmaceutical company names Shirley Liu Clayton chief executive officer
Personnel - Boess named VP, chief financial officer at pharmaceutical firm
Personnel - Brewer named to biotech company's board of directors
Personnel - Device firm announces management team changes
Personnel - Device firm names John Grotting chairman, CEO
Personnel - Hawkins named new CEO at biotech firm
Personnel - Kuo, Sedlack named to board of directors at vaccine development company
Personnel - Medical products company names new senior vice president
Personnel - New member appointed to U.S. Health & Human Services advisory committee
Personnel - Pharmaceutical company announces new chief financial officer
Personnel - Pharmaceutical firm announces promotions, management changes
Personnel - Protein therapeutics company announces additions to management team
Personnel - Systems regulatory compliance company names new VP, quality assurance
Personnel - Venter to chair scientific advisory board at genomics firm
Personnel - Vice chairman at company resigns at clinical lab firm
Postoperative Pain - LogPad electronic patient diary to be used in postop pain clinical trial
Premenstrual Syndrome - New premenstrual syndrome supplement pack launched
Prosthetics - Cadence HP prosthetic foot now rated up to 350 pounds
Protease Inhibitors - Boosted saquinavir demonstrates superior lipid safety profile vs. Kaletra
Proteomics - Phe*-Ala-based pentapeptide mimetics are BACE inhibitors
Psoriasis - Amevive with common treatments improves chronic plaque psoriasis outcome
Psoriasis - U.S. Soriatane (acitretin) product rights acquired from Roche
Psoriatic Arthritis - Remicade shows promising results in psoriatic arthritis study
Quality Assurance - Respiratory products manufacturer receives FDA warning letter
Schizophrenia - Ziprasidone improves cognitive function in schizophrenic patients
Scleroderma - Preliminary results reported from phase I/II trial of Cat-192
Sepsis - Nitric oxide blockade's role in treating septic shock unclear
Sexual Dysfunction - Future pill for premature ejaculation under study
Signaling Networks - Use of its BioMAP technology demonstrated to determine functions of genes
Tissue Engineering - Pioneering techniques may overcome some current challenges
Trends - Market growing for energy-based therapeutic technologies
Venous Leg Ulcers - Frozen OrCel promotes superior healing in venous leg ulcers, study shows
Virology - gp64-Pseudotyped vectors are appealing because of narrower cell attraction
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