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Breast Cancer

Advexin, chemotherapy combination shows promise in treating breast cancer

Published in Biotech Business Week, January 10th, 2005

Introgen Therapeutics, Inc., (INGN) reported data from its phase II trial evaluating Advexin combined with neoadjuvant chemotherapy in women with locally advanced breast cancer.

Neoadjuvant treatments are administered prior to surgery and represent a novel and increasingly applied approach to make surgical tumor resections either more complete improving outcomes or less invasive facilitating breast conservation. Objective clinical responses with a greater than 50% reduction in tumor size were seen following the combined therapy in all of the patients.

Complete tumor removal by subsequent surgery was achieved in 100% of the patients. The results of...

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