Drug Development

Spray-dried emulsions with drug dissolved in lipid characterized

Published in Biotech Business Week, March 7th, 2005

Spray-dried emulsions with a drug dissolved in lipid have been prepared and characterized.

Scientists in Denmark conducted a study "to prepare directly compressible powders, containing a poorly water-soluble drug dissolved in medium-chain triglycerides (MCT), by spray drying o/w-emulsions in a pilot plant spray dryer."

"In addition to the lipid phase, the emulsions contained a water-soluble carrier (a sugar), a water-insoluble carrier (magnesium alumino metasilicate) and a combined emulsifier and film-forming agent (gelatine)," explained T. Hansen and coauthors working at H. Lundbeck A/S.

"A factorial design was used to...

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Source: Biotech Business Week (2005-03-07)

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