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Angina

Company launches phase IIb trial in patients with severe coronary artery disease

Published in Biotech Business Week, March 28th, 2005

GenVec, Inc., (GNVC) announced the launch of a phase IIb randomized, placebo-controlled trial of its BIOBYPASS angiogen for the treatment of severe coronary artery disease.

The NOVA (NOGA Delivery of VEGF for Angina) trial will evaluate the effects of BIOBYPASS on exercise tolerance, heart function, symptoms, and quality of life in approximately 129 patients suffering from moderate-to-severe chest pain due to advanced coronary artery disease.

Jens Kastrup, MD, at Rigshospitalet in Copenhagen, Denmark, is the principal investigator for the NOVA trial. Two medical centers have begun enrollment, under the direction of Dr. Erik Jorgensen at...

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