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HIV/AIDS

Antibody that neutralizes most HIV strains described

Published in Biotech Business Week, March 28th, 2005

A group of scientists from The Scripps Research Institute and several other institutions has solved the structure of a rare human antibody that broadly neutralizes human immunodeficiency virus (HIV), which causes acquired immunodeficiency syndrome (AIDS).

Neutralizing antibodies are soluble proteins that are secreted by adaptive immune cells into the bloodstream, following exposure to a virus. In the bloodstream, antibodies bind to viral particles in circulation, prevent them from infecting human cells, and lead to the viral particles' destruction-thus neutralizing them.

Because neutralizing antibodies attack the virus before it enters cells, they...

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