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Respiratory Medicine

Promising phase II data with inhaled anticholinergic LAS34273 reported

Published in Biotech Business Week, July 25th, 2005

Almirall, a Spanish multinational pharmaceutical company, announced that its development compound LAS34273 has successfully completed a large multicenter phase II study.

The dose-range study assessed efficacy, safety and tolerability of inhaled LAS34273 administered once-daily in patients with moderate to severe stable chronic obstructive pulmonary disease compared with placebo. This large study was composed of a total of 48 centers across seven European countries and it included 464 randomized patients in the trial.

Results demonstrate that LAS34273 has a sustained 24-h bronchodilator effect; an effect that was rapidly observed and was maintained...

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