Published in Biotech Business Week, August 22nd, 2005
Pathway analysis is critical to understanding how target proteins function in the context of the living cell, and can reveal important information about off-target effects, compound specificity, and cross-reactivity for drug candidates.
Traditional approaches for analysis of protein translocation into the nucleus have either relied upon an indirect approach using reporter gene assays, or have involved the use of GFP or antibodies coupled...
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