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Leukemia

Data demonstrate clinical activity of Vidaza with histone deacetylase inhibitors in leukemias

Published in Biotech Business Week, January 8th, 2007

Pharmion Corporation (PHRM) announced new data presented from three studies of Vidaza (azacitidine for injectable suspension) in combination with several histone deacetylase (HDAC) inhibitors, including Pharmion's licensed HDAC inhibitor, MGCD0103.

These studies were presented at the 48th Annual Meeting and Exposition of the American Society of Hematology (ASH) in Orlando.

"It is becoming ever clearer that multiple epigenetic pathways typically operate in parallel to silence tumor suppressor genes in cancer cells," said Dr. Andrew Allen, Pharmion's chief medical officer. "By combining epigenetic therapies, such as DNA demethylating agents and HDAC...

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