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Pharmacology

Study results from Chi-Mei Medical Center, Department of Medical Research in the area of pharmacology published

Published in Biotech Business Week, January 29th, 2007

Research findings, "Dextromethorphan, 3-methoxymorphinan, and dextrorphan have local anaesthetic effect on sciatic nerve blockade in rats," are discussed in a new report. According to a study from Tainan, Taiwan, "Dextromethorphan has been used as an antitussive for more than 40 years and is considered a drug with a good margin of safety. The aim of the study was to evaluate whether dextromethorphan and its metabolites--3-methoxymorphinan and dextrorphan--had local anaesthetic effects."

"Using a method of sciatic nerve blockade in rats, the potencies and durations of actions of dextromethorphan and its metabolites on sciatic nerve blockades of motor function,...

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