Published in Biotech Business Week, January 29th, 2007
Anticipated applications for biomarkers include drug discovery and lead optimization, preclinical and clinical development, patient diagnostics, toxicity testing, targeted therapeutics, and treatment tracking and prognostics.
But before this potential can be fully realized, numerous challenges remain to be solved. Single biomarkers are no longer considered adequate for most anticipated applications - multiple protein panels are the new paradigm. Because of variations in sample complexity, the approach to biomarker discovery will continue to be highly...
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