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Life Sciences
New findings from King's College London, King's College London in the area of life sciences published
January 29th, 2007
New research, "Transesterification of p-hydroxybenzoate esters (parabens) by human intestinal (Caco-2) cells," is the subject of a report. "p-Hydroxybenzoate ester (paraben) preservatives are used in numerous orally administered products. The recognized route of metabolism for parabens is hydrolysis to p-hydroxybenzoic acid followed by conjugation and excretion," scientists in London, the United Kingdom report. "However, in the presence of alcohols, a presystemic transesterification pathway not previously reported for the human intestine can occur. Using human intestinal (Caco-2) cells, it was observed that hydrolysis of parabens to p-hydroxybenzoic acid is reduced...
Source: Biotech Business Week (2007-01-29)
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