Chromatography
New findings in chromatography described from Dr. Reddy's Laboratories Ltd.
Published in Biotech Business Week, March 19th, 2007
A report, "Chiral separation of Frovatriptan isomers by HPLC using amylose based chiral stationary phase," is newly published data in Journal of Chromatography B. "A stereospecific HPLC method for separation of Frovatriptan enantiomers in bulk drug and pharmaceutical formulations was developed and validated on a normal-phase amylose derivertized chiral column. The effects of the organic modifiers namely 2-propanol, ethanol and diethyl amine (DEA) in the mobile phase were optimized to obtain the best enantiomeric separation," scientists writing in the Journal of Chromatography B report.
"Calibration curves were linear over the range of 200-6150 ng/mL, with...
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