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Addiction Medicine

Genes found for successful smoking cessation

Published in Biotech Business Week, April 16th, 2007

Physicians may some day have a new tool for tailoring smoking cessation treatments to a patient's individual genetic makeup.

Researchers from Duke University Medical Center and the National Institute on Drug Abuse scanned the entire genetic makeup, or genome, of smokers and found that variants in 221 genes distinguished smokers who were successful in quitting from those who were not.

"The long-term hope is that identifying these genetic variables in smokers will help us determine which type of treatment would be most effective," said Jed Rose, Ph.D., director of Duke's Center for Nicotine and Smoking Cessation Research. "Knowing a smoker's genetic...

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