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Toxicology

Research results from Osaka City Institute of Public Health and Environmental Science update knowledge of toxicology

Published in Biotech Business Week, April 16th, 2007

New research, "Immunomodulatory effects of mono-, di-, and trimethylphenols in mice," is the subject of a report. According to a study from Osaka, Japan, "The relationship of air pollutants with the increasing prevalence of allergic diseases is a matter of concern in developed countries. In this study, the immunomodulatory effects of mono-, di-, and trimethylphenols in mice were examined as regards two aspects."

"First, whether or not these chemicals act as sensitizers was evaluated by local lymph node assay. Of the 13 methylphenols tested, three dimethylphenol isomers (2,4-DMP, 2,5-DMP, and 3,4-DMP) were found to induce auricular lymphocyte proliferation after dermal...

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