Toxicology
Researchers from Norwegian Institute of Public Health, Division of Environmental Medicine detail new studies and findings in the area of toxicology
Published in Biotech Business Week, April 16th, 2007
Fresh data on toxicology are presented in the report "Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: possible implications for their mutagenic and carcinogenic effects. Nitrated-polycyclic aromatic hydrocarbons (nitro-PAHs) and diesel exhaust particle extracts (DEPE) induced apoptosis in Hepa1c1c7 cells with the following potency: 1,3-dinitropyrene (1,3-DNP) >1-nitropyrene (1-NP) >>DEPE >>1,8-dinitropyrene (1,8-DNP). The compounds induced cyp1a1, and activated various intracellular signalling pathways related to apoptosis," scientists in Nydalen, Norway report.
"The CYP...
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