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Marfan Syndrome
ACE Inhibitor May Help Improve Aortic Stiffness and Dilation Associated With Cardiac Complications From Marfan Syndrome
October 8th, 2007
Preliminary research suggests that use of the ACE inhibitor perindopril, along with a beta-blocker, may help reduce cardiac measures such as aortic stiffness and dilation that are associated with the cardiac complications of Marfan syndrome, according to an article in JAMA. Marfan syndrome (MFS) is a hereditary disorder principally affecting the connective tissues of the body, often characterized by excessive bone elongation and joint flexibility and abnormalities of the eye and cardiovascular system. Progressive aortic dilation and rupture are the most serious complications and the most common cause of premature death. Beta-blockers are currently the standard treatment...
Source: Biotech Business Week (2007-10-08)
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