HIV/AIDS Therapy
New HIV/AIDS therapy study results reported from University of Helsinki, Haartman Institute
Published in Biotech Business Week, January 21st, 2008
Fresh data on HIV/AIDS are presented in the report 'The Vpu-regulated endocytosis of HIV-1 Gag is clathrin-independent.' "Recent results by us and others have shown that the accessory protein Vpu determines plasma membrane versus endosomal accumulation of the HIV-1 core protein Gag and progeny virions in the HeLa model of HIV-1 infection, since Vpu suppresses endocytosis of cell surface-associated Gag. In this report, we used pulse-chase studies and subcellular fractionations to investigate endocytosis of newly synthesized Gag in HeLa H1 cells," scientists in Finland report.
"The uptake of Gag in Delta Vpu-virus background was not blocked by inhibitors of...
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