Life Sciences

New life sciences study findings have been reported by scientists at Baqiyatallah Medical Sciences University

Published in Biotech Business Week, January 21st, 2008

Scientists discuss in 'Paraoxon inhibits GABA uptake in brain synaptosomes' new findings in life sciences. According to a study from Iran, "To investigate possible effect of paraoxon (10(-9)-10(-3)M) on GABA uptake, we used rat cerebral cortex synaptosomes. K(m) and V(max) of GABA uptake were determined in presence of paraoxon (10(-3)M)."

"Acetylcholine and its antagonists (atropine and mecamylamine) were used for evaluating cholinergic-dependency of uptake. Type of transporter involved was determined by using glial (beta-alanine) and neuronal (DABA) GABA uptake inhibitors. The results of the study showed that paraoxon at low doses (10(-9)-10(-6)M) increased and at high...

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Source: Biotech Business Week (2008-01-21)

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