Life Sciences
Oregon State University, Department of Chemistry reports research in life sciences
Published in Biotech Business Week, January 21st, 2008
A report, 'Diels-Alder approach for the construction of halogenated, o-nitro biaryl templates and application to the total synthesis of the anti-HIV agent siamenol,' is newly published data in The Journal of Organic Chemistry. "A rapid Diels-Alder approach to halogenated biaryl templates is described. These biaryl templates are available in two steps from the corresponding aromatic aldehydes," scientists in the United States report.
"The scope of subsequent Suzuki couplings on the biaryl chlorides is explored. Good tolerance for both electron-donating and electron-withdrawing groups in the coupling process can be achieved. Further functionalization of the biaryl...
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