Cardiology

Research from Tel-Aviv University yields new data on cardiology

Published in Biotech Business Week, January 21st, 2008

"Three Popeye domain-containing (Popdc 1-3) family-members are known in vertebrates. Their exact function is as yet unknown although involvement in cell adhesion has been suggested," investigators in Israel report.

"We report herein sequencing of the rat Popdc 1-3 cDNAs that show high homology to other vertebrate orthologs and are expressed primarily in the heart and skeletal muscles. Popdc2 splice variants were identified, with Popdc2C showing a distinctive age-dependent decline," wrote D. Parnes and colleagues, Tel-Aviv University.

The researchers concluded: "In isolated cardiomyocytes, Popdc genes were negatively regulated by serum, an effect that...

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Source: Biotech Business Week (2008-01-21)

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