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American Psychological Association

Rat study suggests why teens get hooked on cocaine more easily than adults

Published in Biotech Business Week, May 5th, 2008

New drug research suggests that teens may get addicted and relapse more easily than adults because developing brains are more powerfully motivated by drug-related cues. This conclusion has been reached by researchers who found that adolescent rats given cocaine – a powerfully addicting stimulant – were more likely than adults to prefer the place where they got it. That learned association endured: Even after experimenters extinguished the drug-linked preference, a small reinstating dose of cocaine appeared to rekindle that preference – but only in the adolescent rats.

The research, performed at McLean Hospital, Harvard Medical School's largest psychiatric facility, was...

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