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Biotech Business Week

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Anxiety Disorders



Research conducted at Columbia University has provided new information about anxiety disorders



May 12th, 2008

"Generalized anxiety disorder (GAD), a prevalent and chronic illness, is associated with dysregulation in both serotonergic and noradrenergic neuro-transmission. Our study examined the efficacy, safety, and tolerability of duloxetine hydrochloride, a dual reuptake inhibitor of serotonin and norepinephrine, for short-term treatment of adults with GAD," investigators in the United States report.

"In a 10-week, double-blind, progressive-titration, flexible-dose trial, 327 adult outpatients with a DSM-IV-defined GAD diagnosis were randomized to duloxetine 60-120 mg (DEX, N = 168) or placebo (PLA, N = 159) treatment. The primary efficacy measure was mean change from baseline...


Source: Biotech Business Week (2008-05-12)

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