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Biotech Business Week

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Breast Cancer



Research data from G. Viale and colleagues update understanding of breast cancer



May 12th, 2008

" To centrally assess estrogen receptor (ER) and progesterone receptor (PgR) levels by immunohistochemistry and investigate their predictive value for benefit of chemo-endocrine compared with endocrine adjuvant therapy alone in two randomized clinical trials for node-negative breast cancer. Patients and Methods International Breast Cancer Study Group Trial VIII compared cyclophosphamide, methotrexate, and fluorouracil (CMF) chemotherapy for 6 cycles followed by endocrine therapy with goserelin with either modality alone in pre- and perimenopausal patients," scientists writing in the Journal of Clinical Oncology report.

"Trial IX compared three cycles of CMF...


Source: Biotech Business Week (2008-05-12)

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