Scripps Research Institute
Scripps Research scientists find seizure drug reverses cellular effects
Published in Biotech Business Week, June 9th, 2008
In the new research, published in the May 28, 2008 edition of The Journal of Neuroscience, the scientists found that gabapentin normalizes the action of certain brain cells altered by chronic alcohol abuse in an area of the brain known as the central amygdala, which plays an important role in fear- and stress-related behaviors, as well as in regulating alcohol drinking. In the study, alcohol-dependent rodents receiving gabapentin drank less alcohol.
"The results are exciting," said Scripps Research Assistant Professor Marisa Roberto, Ph.D., who was first author of the study. "Our research shows that gabapentin not only changes the alcohol-consumption patterns of...
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