Research from Georgetown University, Department of Pharmacology in the area of pharmacology published

Investigators publish new data in the report 'Dual neurotoxic and neuroprotective role of metabotropic glutamate receptor 1 in conditions of trophic deprivation - possible role as a dependence receptor.' According to recent research published in the journal Neuropharmacology, "Group I metabotropic glutamate receptors have been often implicated in various models of neuronal toxicity, however, the role played by the individual receptors and their putative mechanisms of action contributing to neurotoxicity or neuroprotection remain unclear. Here, using primary cultures of rat cerebellar granule cells and mouse cortical neurons, we show that conditions of trophic deprivation increased...

Want to see the full article?

• Purchase this article for only $3.00