University of California - Davis - Health System
UC Davis researchers discover new drug target for inflammatory disease
Published in Biotech Business Week, October 20th, 2008
The scientists discovered that a protein called sPLA2-IIA binds to two integrins labeled alpha-V-beta-3 and alpha-4-beta-1, causing them to rapidly multiply and boosting an immune system response already gone awry due to disease.
"We have known for a while that this protein is elevated with inflammation," said Yoshikazu Takada, UC Davis professor of dermatology and lead author of the...
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