Published in Biotech Business Week, November 24th, 2008
"We conducted a randomized, double-blind, pharmacogenetic study of behavioral therapy and sibutramine (10 or 15 mg daily) or placebo for 12 weeks in 181 overweight or obese participants. We measured body weight, body mass index, body composition, gastric emptying, and genetic variation (alpha 2A C1291G, 5-HTTLPR, and GN beta 3 C825T genotypes). Analysis of covariance was used to assess...
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