Life Sciences
Findings from University of Minnesota advance knowledge in life sciences
Published in Biotech Business Week, December 15th, 2008
"Although population-based association mapping may be subject to the bias caused by population stratification, alternative methods that are robust to population stratification such as family-based linkage analysis have lower mapping resolution. Recently, various statistical methods robust to population stratification were proposed for association studies, using unrelated individuals to identify associations between candidate genes and traits of interest," investigators in the United States report.
"The association between a candidate gene and a quantitative trait is often evaluated via a regression model with inferred population structure variables as covariates, where...
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