Skin Cancer
New skin cancer research has been reported by J. Schenkel et al
Published in Biotech Business Week, January 5th, 2009
"Both contain stem cells targeted by carcinogens upon initiation of mouse skin carcinogenesis. It is unknown whether the anti-apoptotic activity, of BCL-2 is involved in the susceptibility of this cell type to malignant transformation. If so, extending the pool of BCL-2-expressing cells to suprabasal skin layers should increase the likelihood of skin tumour formation. To resolve this issue, we generated a novel transgenic mouse line overexpressing...
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