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Cancer Therapy

Reports summarize cancer therapy research from National Institutes of Health

Published in Biotech Business Week, January 5th, 2009

New research, 'Inhibition of Mammalian target of rapamycin by rapamycin causes the regression of carcinogen-induced skin tumor lesions,' is the subject of a report. According to recent research from the United States, "The activation of Akt/mammalian target of rapamycin (mTOR) pathway represents a frequent event in squamous cell carcinoma (SCC) progression, thus raising the possibility of using specific mTOR inhibitors for the treatment of SCC patients. In this regard, blockade of mTOR with rapamycin prevents the growth of human head and neck SCC cells when xenotransplanted into immunodeficient mice."

"However, therapeutic responses in xenograft tumors are not always...

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