Heart Disease
Research reports on heart disease from X.L. Liu and colleagues provide new insights
Published in Biotech Business Week, January 5th, 2009
"Dyslipidemia, especially hypercholesterolemia, is a mal. or risk factor of coronary heart disease (CHD).The insulin induced gene 1 (INSIG1) and insulin induced gene 2 (INSIG2) encode two proteins which mediate feedback control of cholesterol synthesis. We conducted a case-control study to investigate whether the common variants in INSIG genes were associated with CHD in Chinese Han population," scientists in Beijing, People's Republic of China report.
"Three single nucleotide polymorphisms (SNPs) of the INSIG 1 gene and four SNPs of the INSIG2 gene were chosen as haplotype-tagging SNPs (htSNPs) and genotyped in 853 patients with CHD and 948 unrelated control subjects....
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