Ulcerative Colitis
New findings from Semmelweis University in the area of ulcerative colitis described
Published in Biotech Business Week, March 16th, 2009
According to recent research from Budapest, Hungary, " In previous studies the NFKBIA 3'alleles did not predict response to medical therapy or need for surgery.UTR (untranslated region) AA genotype was associated with Crohn's disease (CD), while the NFKB1-94ins/del-ATTG mutation increased the risk for ulcerative colitis (UC). The aim of our study was to investigate these two polymorphisms and patients' response to medical therapy and/or disease phenotype in Hungarian inflammatory bowel disease (IBD) patients."
" NFKBIA 3'UTR- and NFKB1-94ins/delATTG polymorphisms were investigated in 415 unrelated IBD patients (CD: 266 patients, mean age 35.2 +/- 12.1 years, duration...
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