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Insecticidal toxin useless without 'friendly' bacteria accomplices

Published in Biotech Business Week, March 16th, 2009

The toxin produced by the bacterium Bacillus thuringiensis (Bt) is a popular insecticide used to control pest moths and butterflies, and in some GM pest-proof crops. In a study published in the open access journal BMC Biology, researchers show that its effectiveness against a number of susceptible Lepidopteran species depends on the presence of the normally "friendly" bacteria that colonise their guts. Without these bacteria, the Bt toxin can become impotent in some species.

A team of researchers from the University of Wisconsin studied the effects of wiping out the commensal gut bacteria using antibiotics in six moth and butterfly species. In five of these species, the...

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