Monoclonal Antibodies
Researchers at University of Lille publish new data on monoclonal antibodies
Published in Biotech Business Week, July 6th, 2009
In this recent report, researchers in Lille, France conducted a study "To compare outcomes of induction dosing followed by continuous adalimumab treatment with those of induction dosing with reinitiation of adalimumab (in the event of clinical deterioration) for patients with moderate-to-severe Crohn's disease (CD) who participated in the Crohn's Trial of the Fully Human Antibody Adalimumab for Remission Maintenance (CHARM). In the CHARM trial, all patients received open-label induction therapy with adalimumab 80 mg and 40 mg at weeks 0 and 2, respectively."
"In total, 778 patients were randomized at week 4 to one of three groups: (1) placebo after initial induction...
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