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Enzyme Research
Study findings on enzyme research are outlined in reports from Medical College, Medical Department
July 6th, 2009
"Cisplatin is a highly effective chemotherapeutic agent against many tumors; however, it is also a potent nephrotoxicant. Given that there have been no significant advances in our ability to clinically manage acute renal failure since the advent of dialysis, the development of novel strategies to ablate nephrotoxicity would represent a significant development," scientists writing in the journal Cell Biology and Toxicology report. "In this study, we investigated the ability of an inhibitor of soluble epoxide hydrolase (sEH), n-butyl ester of 12-(3-adamantan-1-yl-ureiido)-dodecanoic acid (nbAUDA), to attenuate cisplatin-induced nephrotoxicity. nbAUDA is quickly...
Source: Biotech Business Week (2009-07-06)
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